Article
Sustained persistence of blockade antibodies against emerging GII.4 and GII.17 noroviruses revealed by a 5-year community-based serological study.
Frontiers in cellular and infection microbiology - 1 Jan 2026
Xie Dong-Jie, Zhang Yu, Zhou Fei-Yuan, Koroma Mark Momoh, Liang Zhi-Yan, Zhang Xu-Fu, Dai Ying-Chun
Abstract excerpt
Introduction: GII noroviruses (NoVs) are the leading cause of viral gastroenteritis worldwide. A critical unresolved question is whether natural infection elicits long-lasting protective antibodies, which is paramount for guiding vaccine development. The long-term persistence of functional neutralizing antibodies against the predominant GII genogroup remains poorly characterized. Methods: In a 5-year...
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