Article
Emergence of a novel GII.17 variant is associated with immune evasion rather than an altered HBGA-binding profile.
PLoS pathogens - 1 Aug 2026
van der Krieken Stefan T, Morais Esteves Francisco, Villabruna Nele, Schapendonk Claudia M E, Izquierdo-Lara Ray W, Fajar Putri Ayu, Leijten Lonneke, de Jong Anja, Koning Roman I, Doukas Michail C, GeurtsvanKessel Corine H, Koopmans Marion P G, de Graaf Miranda
Abstract excerpt
The epidemiology of noroviruses, a major cause of gastroenteritis in humans, is shaped by their continuous evolution. Novel genotypes and variants periodically emerge, replacing previously dominant strains. In 2024, a novel GII.17 variant led to an increased number of notified outbreaks, becoming the dominant genotype detected in Europe. To investigate if this surge in GII.17 detection is attributable to changes...
Read the complete abstract on PubMedTopics
- Humans
- Immune Evasion
- Norovirus
- Blood Group Antigens
- Caliciviridae Infections