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Article

Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice.

Archives of toxicology - 1 Apr 2012

Weng Zuquan, Suda Megumi, Ohtani Katsumi, Mei Nan, Kawamoto Toshihiro, Nakajima Tamie, Wang Rui-Sheng

Abstract excerpt

Ethyl tertiary butyl ether (ETBE) is used as an additive to gasoline to reduce carbon monoxide emissions in some developed countries. So far, ETBE was not found with positive results in many genotoxic assays. This study is undertaken to investigate the modifying effects of deficiency of aldehyde dehydrogenase 2 (ALDH2) on the toxicity of ETBE in the livers of mice. Eight-week-old wild-type (WT) and Aldh2 knockout...

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Source

Identifiers

PMID: 22102104
DOI: 10.1007/s00204-011-0779-x

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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