Article
Beta Adrenoceptor Polymorphism and Clinical Response to Sertraline in Major Depressive Patients.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques - 1 Jan 2017
Firouzabadi Negar, Raeesi Roshanak, Zomorrodian Kamiar, Bahramali Ehsan, Yavarian Ilnaz
Abstract excerpt
PURPOSE: The adrenoceptor family, as one of the main contributors in regulating the noradrenergic system, has been studied in involvement of depression and its treatment. A functional polymorphism of G1165C on beta adrenoceptor (βAR) enhances post receptor signalling and is assumed to be involved in pharmacotherapy of depression. The aim of the present study was to discern the influence of G1165C polymorphism in...
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