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Article

Influence of ACE gene on differential response to sertraline versus fluoxetine in patients with major depression: a randomized controlled trial.

European journal of clinical pharmacology - 1 Sept 2016

Bahramali Ehsan, Firouzabadi Negar, Yavarian Ilnaz, Shayesteh Mohammad Reza Hooshangi, Erfani Nasrallah, Shoushtari Ali Alavi, Asadpour Roja

Abstract excerpt

BACKGROUND: Extensive distribution of the different components of renin angiotensin system (RAS) in the brain, along with their roles in promoting anxiety, depression and brain inflammation, opposes RAS as a potential therapeutic target in major depression. Actions of angiotensin II, the main product of RAS, are reduced by antidepressants and this signifies the complex interplay of different mechanisms involved...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27262302
DOI: 10.1007/s00228-016-2079-0

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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