Article
Serotonergic receptor gene polymorphism and response to selective serotonin reuptake inhibitors in ethnic Malay patients with first episode of major depressive disorder.
The pharmacogenomics journal - 1 Aug 2021
Badamasi Ibrahim Mohammed, Lye Munn Sann, Ibrahim Normala, Abdul Razaq Nurul Asyikin, Ling King Hwa, Stanslas Johnson
Abstract excerpt
The polymorphisms of the 5HTR1A and 5HTR2A receptor genes (rs6295C/G and rs6311G/A) have been evaluated for association with SSRI treatment outcome in various populations with different results. The present study was carried out to determine the association between genotypes of HTR1A-rs6295 and HTR2A-rs6311 with SSRI treatment outcome among the ethnic Malay patients diagnosed with first-episode major depressive...
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