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Article

Association between the 5-HT1A receptor gene polymorphism (rs6295) and antidepressants: a meta-analysis.

International clinical psychopharmacology - 1 Nov 2012

Zhao Xiaofeng, Huang Yinglin, Li Jingying, Ma Hui, Jin Qiu, Wang Yuan, Wu Lijuan, Zhu Gang

Abstract excerpt

Previous studies have implicated 5-HT1A receptor gene (HTR1A) polymorphisms in the therapeutic response to antidepressants, especially selective serotonin reuptake inhibitors. A functional HTR1A C-1019G polymorphism (rs6295) in the promoter region was found to be associated with antidepressant pharmacogenetics in different populations. However, inconsistent and inconclusive results have been obtained. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22890315
DOI: 10.1097/YIC.0b013e32835818bf

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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