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Article

Effect of 5-HT1A gene polymorphisms on antidepressant response in major depressive disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2009

Kato Masaki, Fukuda Tsuyoshi, Wakeno Masataka, Okugawa Gaku, Takekita Yoshiteru, Watanabe Syunsuke, Yamashita Megumi, Hosoi Yuka, Azuma Junichi, Kinoshita Toshihiko, Serretti Alessandro

Abstract excerpt

Variability in antidepressant response is due to genetic and environmental factors. Among genetic factors, the ones controlling for availability of the drug at the target site are interesting candidates. Rs6295C/G SNP in the 5-HT1A gene (HTR1A) has been found to affect the expression and function of HTR1A. In fact rs6295C/G is in strong linkage disequilibrium with other polymorphisms of HTR1A suggesting that...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptor, Serotonin, 5-HT1A

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PMID: 18484082
DOI: 10.1002/ajmg.b.30783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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