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Article

CRISPR/Cas9-Mediated Gene Targeting during Embryogenesis in Swine.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Ryu Junghyun, Lee Kiho

Abstract excerpt

Ability to disrupt genes is essential in elucidating gene function. Unlike rodents or amphibians, it has been difficult to generate gene-targeted embryos in large animals. Therefore, studies of early embryo development have been hampered in large animals. A recent technology suggests that targeted mutations can be successfully introduced during embryogenesis, thus by-passing the need of breeding to produce...

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Share to Animals, Genetically Modified
Share to CRISPR-Cas Systems
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28456969
DOI: 10.1007/978-1-4939-6988-3_16
PMCID: PMC6205924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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