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Article

Regulation of neuromuscular junction organization by Rab2 and its effector ICA69 in Drosophila.

Development (Cambridge, England) - 1 Jun 2017

Mallik Bhagaban, Dwivedi Manish Kumar, Mushtaq Zeeshan, Kumari Manisha, Verma Praveen Kumar, Kumar Vimlesh

Abstract excerpt

The mechanisms underlying synaptic differentiation, which involves neuronal membrane and cytoskeletal remodeling, are not completely understood. We performed a targeted RNAi-mediated screen of Drosophila BAR-domain proteins and identified islet cell autoantigen 69 kDa (ICA69) as one of the key regulators of morphological differentiation of the larval neuromuscular junction (NMJ). We show that Drosophila ICA69...

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Identifiers

PMID: 28455372
DOI: 10.1242/dev.145920

Genes

PICK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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