Article
ciBAR1 loss in mice causes laterality defects, pancreatic degeneration, and altered glucose tolerance.
Life science alliance - 1 Feb 2025
Kim Eunice N, Li Feng-Qian, Takemaru Ken-Ichi
Abstract excerpt
Bin/Amphiphysin/Rvs (BAR) domains are highly conserved domains found in all eukaryotes. BAR domain proteins form crescent-shaped dimers that sense and sculpt curved lipid membranes and play key roles in various cellular processes. However, their functions in mammalian development are poorly understood. We previously demonstrated that Chibby1-interacting BAR domain-containing 1 (ciBAR1, formerly known as FAM92A)...
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