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Article

APOEε4 Genotype and Hypertension Modify 8-year Cortical Thinning: Five Occasion Evidence from the Seattle Longitudinal Study.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jun 2018

Rast Philippe, Kennedy Kristen M, Rodrigue Karen M, Robinson Paul R A W, Gross Alden L, McLaren Donald G, Grabowski Tom, Schaie K Warner, Willis Sherry L

Abstract excerpt

We investigated individual differences in longitudinal trajectories of brain aging in cognitively normal healthy adults from the Seattle Longitudinal Study covering 8 years of longitudinal change (across 5 occasions) in cortical thickness in 249 midlife and older adults (52-95 years old). We aimed to understand true brain change; examine the influence of salient risk factors that modify an individual's rate of...

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Identifiers

PMID: 28444388
DOI: 10.1093/cercor/bhx099
PMCID: PMC6019039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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