Article
Molecular characterisation of extensively drug-resistant Mycobacterium tuberculosis isolates in China.
International journal of antimicrobial agents - 1 Feb 2015
Zhao Li-li, Sun Qing, Zeng Chun-yan, Chen Yan, Zhao Bing, Liu Hai-can, Xia Qiang, Zhao Xiu-qin, Jiao Wei-wei, Li Gui-lian, Wan Kang-lin
Abstract excerpt
The emergence of extensively drug-resistant tuberculosis (XDR-TB) in China is a great threat to TB control. To determine the molecular characterisation of XDR-TB isolates from China and the correlations between specific drug resistance-associated mutations and different genotype strains, 58 XDR-TB isolates were sequenced in eight drug loci, including katG, inhA, oxyR-ahpC intergenic region, rpoB, eis, rrs, gyrA...
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