Article
Comparison of the MeltPro TB assay and whole-genome sequencing assay for rapid molecular diagnosis of drug resistant tuberculosis in guangdong province.
Diagnostic microbiology and infectious disease - 1 Feb 2024
Yu Meiling, Zhang Chenchen, Xu Liuyue, Peng Kehao, Qiu Haoqing, Zhuo Wenji, Zhao Yuchuan, Wu Zhuhua, Chen Xunxun, Chen Yanmei, Liao Qinghua, Huang Yinna, Wei Wenjing
Abstract excerpt
BACKGROUND: Rifampicin (RIF) and multidrug-resistant tuberculosis (TB) are major public health threats. As conventional phenotypic drug susceptibility testing requires two-eight weeks, molecular diagnostic assays are widely used to determine drug resistance. METHODS: Clinical Mycobacterium tuberculosis isolates with consistent drug susceptibility results, tested using microbroth dilution and proportion methods in...
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