Comprehensive assessment showed no associations of variants at the SLC10A1 locus with susceptibility to persistent HBV infection among Southern Chinese.

doi:10.1038/srep46490

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Article

Comprehensive assessment showed no associations of variants at the SLC10A1 locus with susceptibility to persistent HBV infection among Southern Chinese.

Scientific reports - 21 Apr 2017

Zhang Ying, Li Yuanfeng, Wu Miantao, Cao Pengbo, Liu Xiaomin, Ren Qian, Zhai Yun, Xie Bobo, Hu Yanling, Hu Zhibin, Bei Jinxin, Ping Jie, Liu Xinyi, Yu Yinghua, Guo Bingqian, Lu Hui, Liu Guanjun, Zhang Haitao, Cui Ying, Mo Zengnan, Shen Hongbing, Zeng Yi-Xin, He Fuchu, Zhang Hongxing, Zhou Gangqiao

Abstract excerpt

The sodium taurocholate cotransporting polypeptide (NTCP) encoded by SLC10A1 was recently demonstrated to be a functional receptor for hepatitis B virus (HBV). The role of SLC10A1 polymorphisms, particularly the Ser267Phe variant (rs2296651) in exon 4, has been frequently investigated in regard to risk of persistent HBV infection. However, these investigations have generated conflicting results. To examine...

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PMID: 28429786
DOI: 10.1038/srep46490
PMCID: PMC5399367

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