Correlations between ASCC3 Gene Polymorphisms and Chronic Hepatitis B in a Chinese Han Population.

doi:10.1371/journal.pone.0141861

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Article

Correlations between ASCC3 Gene Polymorphisms and Chronic Hepatitis B in a Chinese Han Population.

PloS one - 1 Jan 2015

Liu Lifeng, Zhang Jinliang, Lu Yan, Fang Chunfang, Li Senlin, Lin Jusheng

Abstract excerpt

We have previously identified 8 SNPs in Han Chinese HBV carriers that are associated with disease progression. Although not well studied, genetic factors may also play a significant role in developing chronic HBV disease after exposure. We extend the effect of these eight SNPs on persistent HBV infection in this study. A total of 875 unrelated Han Chinese, 493 chronic hepatitis B subjects (CHB) and 382 HBV...

Topics

Adult
Biomarkers
Case-Control Studies
China
DNA Helicases
Female
Follow-Up Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Hepatitis B virus
Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Incidence

Male

Middle Aged

Polymorphism, Single Nucleotide

Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 26536629
DOI: 10.1371/journal.pone.0141861
PMCID: PMC4633062

Genes

ASCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26536629-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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