Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register.

EBioMedicine - 1 Apr 2017

Hilker Rikke, Helenius Dorte, Fagerlund Birgitte, Skytthe Axel, Christensen Kaare, Werge Thomas M, Nordentoft Merete, Glenthøj Birte

Abstract excerpt

BACKGROUND: Early age at illness onset has been viewed as an important liability marker for schizophrenia, which may be associated with an increased genetic vulnerability. A twin approach can be valuable, because it allows for the investigation of specific illness markers in individuals with a shared genetic background. METHODS: We linked nationwide registers to identify a cohort of twin pairs born in Denmark...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Denmark

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proportional Hazards Models

Share to Registries

Share to Risk Factors

Share to Schizophrenia

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28427946
DOI: 10.1016/j.ebiom.2017.04.002
PMCID: PMC5405190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register.PMID 28427946Read ↗

The genetic basis of onset age in schizophrenia: evidence and modelsSemantic proximity Read ↗

Genetic loci associated with an earlier age at onset in multiplex schizophrenia.Semantic proximity Read ↗

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women.Semantic proximity Read ↗

Association of older paternal age with earlier onset among co-affected schizophrenia sib-pairs.Semantic proximity Read ↗

Genetic modifiers and subtypes in schizophrenia: investigations of age at onset, severity, sex and family history.Semantic proximity Read ↗

Parental age and risk of schizophrenia: a case-control study.Semantic proximity Read ↗

Genome-wide association analysis of age at onset in schizophrenia in a European-American sample.Semantic proximity Read ↗

Heritability of schizophrenia and major affective disorder as a function of age, in the presence of strong cohort effects.Semantic proximity Read ↗

Why does age of onset predict clinical severity in schizophrenia? A multiplex extended pedigree studySemantic proximity Read ↗

Common genetic variants contribute to heritability of age at onset of schizophreniaSemantic proximity Read ↗

A genomewide linkage study of age at onset in schizophrenia.Semantic proximity Read ↗

A typological model of schizophrenia based on age at onset, sex and familial morbidity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.