Article
A genomewide linkage study of age at onset in schizophrenia.
American journal of medical genetics - 8 Jul 2001
Cardno A G, Holmans P A, Rees M I, Jones L A, McCarthy G M, Hamshere M L, Williams N M, Norton N, Williams H J, Fenton I, Murphy K C, Sanders R D, Gray M Y, O'Donovan M C, McGuffin P, Owen M J
Abstract excerpt
There is strong evidence for a genetic contribution to age at onset of schizophrenia, which probably involves both susceptibility loci for schizophrenia and modifying loci acting independent of disease risk. We sought evidence of linkage to loci that influence age at onset of schizophrenia in a sample of 94 affected sibling pairs with DSM-IV schizophrenia or schizoaffective disorder, and age at first psychiatric...
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