Article
Heritability of schizophrenia and major affective disorder as a function of age, in the presence of strong cohort effects.
European archives of psychiatry and clinical neuroscience - 1 Jun 2006
Husted Janice A, Greenwood Celia M T, Bassett Anne S
Abstract excerpt
It remains unclear whether age at onset for major psychiatric disorders is a useful marker of etiologic and genetic heterogeneity. The authors examined how heritability of schizophrenia and major affective disorders varied with age at onset. The sample was drawn from a large archival data set collected by Lionel Penrose, comprising 3,109 families with two or more members first hospitalized in Ontario between 1874...
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