Article
Herpesvirus active replication in multiple sclerosis: a genetic control?
Journal of the neurological sciences - 15 Dec 2011
Garcia-Montojo Marta, Martinez Alfonso, De Las Heras Virginia, Dominguez-Mozo Maria Inmaculada, Cenit Maria del Carmen, López-Cavanillas Maria, Garcia-Martinez Angel, Arias-Leal Ana Maria, Gomez de la Concha Emilio, Urcelay Elena, Arroyo Rafael, Alvarez-Lafuente Roberto
Abstract excerpt
Although the etiology of multiple sclerosis (MS) is unknown, it is generally believed that genetic, immunologic, and environmental factors are involved. The objectives of this study were: 1. to analyze if a genetic control could explain why HHV-6 would be able to actively replicate in a subset of MS patients but not in controls; 2. to study if MS patients with HHV-6 active replication are clinically different...
Topics
- Adult
- Cohort Studies
- Comorbidity
- Drug Resistance
- Female
- Gene-Environment Interaction
- Genetic Predisposition to Disease
- Herpesvirus 6, Human
- Humans
- Male