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Article

Genetic Variant HLA-DRB1*0403 and Therapeutic Response to Disease-Modifying Therapies in Multiple Sclerosis: A Case-Control Study.

International journal of molecular sciences - 27 Sept 2023

Gomez-Gaitan Esteban Alejandro, Garcia-Ortega Yessica Eleanet, Saldaña-Cruz Ana Miriam, Contreras-Haro Betsabe, Gamez-Nava Jorge Ivan, Perez-Guerrero Emilio Edsaul, Nava-Valdivia Cesar Arturo, Gallardo-Moya Sergio, Martinez-Hernandez Alejandra, Gonzalez Lopez Laura, Rios-Gonzalez Blanca Esthela, Marquez-Pedroza Jazmin, Mendez-Del Villar Miriam, Esparza-Guerrero Yussef, Villagomez-Vega Alejandra, Macias Islas Miguel Angel

Abstract excerpt

Multiple sclerosis (MS) is a chronic and demyelinating disease with an autoimmune origin, which leads to neurodegeneration and progressive disability. Approximately 30 to 50% of patients do not respond optimally to disease-modifying therapies (DMTs), and therapeutic response may be influenced by genetic factors such as genetic variants. Therefore, our study aimed to investigate the association of the...

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Identifiers

PMID: 37834042
DOI: 10.3390/ijms241914594
PMCID: PMC10572793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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