Article
Diversity of the association of serum levels and genetic variants of MHC class I polypeptide-related chain A with liver fibrosis in chronic hepatitis C.
Oncotarget - 16 May 2017
Huang Chung-Feng, Huang Ching-I, Yeh Ming-Lun, Wang Shu-Chi, Chen Kuan-Yu, Ko Yu-Min, Lin Ching-Chih, Tsai Yi-Shan, Tsai Pei-Chien, Lin Zu-Yau, Chen Shinn-Cherng, Dai Chia-Yen, Huang Jee-Fu, Chuang Wan-Long, Yu Ming-Lung
Abstract excerpt
BACKGROUND/AIMS: Genetic variants of MHC class I polypeptide-related chain A (MICA) at rs2596542 have been associated with hepatocellular carcinoma. The linkage between serum MICA (sMICA) and liver fibrosis in chronic hepatitis C is elusive. RESULTS: Linear regression analysis revealed that sMICA were independently correlated to α-fetoprotein (β: 0.149; 95% confidence interval [CI]: 0.001, 0.003; P = 0.007)and...
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