Article
Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment.
EBioMedicine - 1 Feb 2017
Huang Chung-Feng, Huang Cing-Yi, Yeh Ming-Lun, Wang Shu-Chi, Chen Kuan-Yu, Ko Yu-Min, Lin Ching-Chih, Tsai Yi-Shan, Tsai Pei-Chien, Lin Zu-Yau, Chen Shinn-Cherng, Dai Chia-Yen, Huang Jee-Fu, Chuang Wan-Long, Yu Ming-Lung
Abstract excerpt
BACKGROUND/AIMS: The genome-wide association study has shown that MHC class I chain-related A (MICA) genetic variants were associated with hepatitis C virus (HCV) related hepatocellular carcinoma (HCC). The impact of the genetic variants and its serum levels on post-treatment cohort is elusive [corrected]. METHODS: MICA rs2596542 genotype and serum MICA (sMICA) levels were evaluated in 705 patients receiving...
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