Article
Association of MICA gene polymorphisms with liver fibrosis in schistosomiasis patients in the Dongting Lake region.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Mar 2012
Gong Zheng, Luo Qi-Zhi, Lin Lin, Su Yu-Ping, Peng Hai-Bo, Du Kun, Yu Ping, Wang Shi-Ping
Abstract excerpt
Major histocompatibility complex class I chain-related A (MICA) is a highly polymorphic gene located within the MHC class I region of the human genome. Expressed as a cell surface glycoprotein, MICA modulates immune surveillance by binding to its cognate receptor on natural killer cells, NKG2D, and its genetic polymorphisms have been recently associated with susceptibility to some infectious diseases. We...
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