Article
Genetic variation at -1878 (rs2596542) in MICA gene region is associated with chronic hepatitis B virus infection in Saudi Arabian patients.
Experimental and molecular pathology - 1 Dec 2013
Al-Qahtani Ahmed A, Al-Anazi Mashael, Abdo Ayman A, Sanai Faisal M, Al-Hamoudi Waleed, Alswat Khalid A, Al-Ashgar Hamad I, Khalaf Nisreen, Viswan Nisha, Al-Ahdal Mohammed N
Abstract excerpt
MHC class I polypeptide-related chain A (MICA), mapping to 6p21.33, belongs to the non-classical class I family and its expression is induced by several stress factors including viral infection. A recent genome-wide association study has identified a single nucleotide polymorphism (SNP) of MICA, rs2596542 to be significantly associated with hepatitis C-induced hepatocellular carcinoma (HCC) in a Japanese...
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