Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma.

Scientific reports - 19 Sept 2017

Hai Hoang, Tamori Akihiro, Thuy Le Thi Thanh, Yoshida Kanako, Hagihara Atsushi, Kawamura Etsushi, Uchida-Kobayashi Sawako, Morikawa Hiroyasu, Enomoto Masaru, Murakami Yoshiki, Kawada Norifumi

Abstract excerpt

Recently, the MICA rs2596542 and DEPDC5 rs1012068 variants in Japanese individuals as well as the HCP5 rs2244546 and PNPLA3 rs738409 variants in European individuals have been found associated with hepatocellular carcinoma (HCC). The present study determined which single nucleotide polymorphism (SNP) is the most predictive for developing hepatitis C virus (HCV)-related HCC in a Japanese cohort. Of the 4 SNPs...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to GTPase-Activating Proteins
Share to Hepatitis C, Chronic
Share to Histocompatibility Antigens Class I
Share to Lipase
Share to Liver Neoplasms
Share to Repressor Proteins
Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 28928439
DOI: 10.1038/s41598-017-10363-5
PMCID: PMC5605683

Genes

MICA
DEPDC5
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma.PMID 28928439Read ↗

A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanismsSemantic proximity Read ↗

[Hepatitis C virus induced hepatocellular carcinoma associated genes].Semantic proximity Read ↗

Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.Semantic proximity Read ↗

Variations in DEPDC5 gene and its association with chronic hepatitis C virus infection in Saudi Arabia.Semantic proximity Read ↗

Hepatocellular carcinoma: Towards personalized medicineSemantic proximity Read ↗

DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection.Semantic proximity Read ↗

Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

Comparative genetic analyses point to HCP5 as susceptibility locus for HCV-associated hepatocellular carcinoma.Semantic proximity Read ↗

Association Between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample.Semantic proximity Read ↗

Genetics Variants and Serum Levels of MHC Class I Chain-related A in Predicting Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients Post Antiviral Treatment.Semantic proximity Read ↗

Genetic variation at -1878 (rs2596542) in MICA gene region is associated with chronic hepatitis B virus infection in Saudi Arabian patients.Semantic proximity Read ↗

Characterizing key nucleotide polymorphisms of hepatitis C virus-disease associations via mass-spectrometric genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.