Article
Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma.
PloS one - 1 Jan 2012
Kumar Vinod, Yi Lo Paulisally Hau, Sawai Hiromi, Kato Naoya, Takahashi Atsushi, Deng Zhenzhong, Urabe Yuji, Mbarek Hamdi, Tokunaga Katsushi, Tanaka Yasuhito, Sugiyama Masaya, Mizokami Masashi, Muroyama Ryosuke, Tateishi Ryosuke, Omata Masao, Koike Kazuhiko, Tanikawa Chizu, Kamatani Naoyuki, Kubo Michiaki, Nakamura Yusuke, Matsuda Koichi
Abstract excerpt
MHC class I polypeptide-related chain A (MICA) molecule is induced in response to viral infection and various types of stress. We recently reported that a single nucleotide polymorphism (SNP) rs2596542 located in the MICA promoter region was significantly associated with the risk for hepatitis C virus (HCV)-induced hepatocellular carcinoma (HCC) and also with serum levels of soluble MICA (sMICA). In this study,...
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