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Article

Associations between MICA and MICB Genetic Variants, Protein Levels, and Colorectal Cancer: Atherosclerosis Risk in Communities (ARIC).

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2023

Wang Shuo, Onyeaghala Guillaume C, Pankratz Nathan, Nelson Heather H, Thyagarajan Bharat, Tang Weihong, Norby Faye L, Ugoji Chinenye, Joshu Corinne E, Gomez Christian R, Couper David J, Coresh Josef, Platz Elizabeth A, Prizment Anna E

Abstract excerpt

BACKGROUND: The MHC class I chain-related protein A (MICA) and protein B (MICB) participate in tumor immunosurveillance and may be important in colorectal cancer, but have not been examined in colorectal cancer development. METHODS: sMICA and sMICB blood levels were measured by SomaScan in Visit 2 (1990-92, baseline) and Visit 3 (1993-95) samples in cancer-free participants in the Atherosclerosis Risk in...

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Identifiers

PMID: 36958849
DOI: 10.1158/1055-9965.EPI-22-1113
PMCID: PMC10239349

Genes

MICA
MICB
IMPACT

Provenance

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