Article
Association of BRM promoter polymorphisms and esophageal adenocarcinoma outcome.
Oncotarget - 25 Apr 2017
Korpanty Grzegorz J, Eng Lawson, Qiu Xin, Faluyi Olusola Olusesan, Renouf Daniel J, Cheng Dangxiao, Patel Devalben, Chen Zhuo, Tse Brandon C, Knox Jennifer J, Dodbiba Lorin, Teichman Jennifer, Azad Abul Kalam, Wong Rebecca, Darling Gail, Reisman David, Cuffe Sinead, Liu Geoffrey, Xu Wei
Abstract excerpt
PURPOSE: Brahma (BRM) is a critical catalytic subunit of the SWI/SNF chromatin remodeling complex; expression of BRM is commonly lost in various cancer types. BRM promoter polymorphisms (BRM-741; BRM-1321) are associated with loss of BRM expression, and with cancer risk/survival. We evaluated these two polymorphisms in the overall survival (OS) of esophageal adenocarcinoma (EAC) patients. RESULTS: Of 270...
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