Article
Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Jan 2013
Endo Mio, Yasui Kohichiroh, Zen Yoh, Gen Yasuyuki, Zen Keika, Tsuji Kazuhiro, Dohi Osamu, Mitsuyoshi Hironori, Tanaka Shinji, Taniwaki Masafumi, Nakanuma Yasuni, Arii Shigeki, Yoshikawa Toshikazu
Abstract excerpt
BACKGROUND: The SWI/SNF chromatin remodelling complex, which contains either brahma-related gene-1 (BRG1) or brahma (BRM) as the catalytic ATPase, functions as a master regulator of gene expression. AIMS: To examine alterations of BRG1 and BRM in hepatocellular carcinoma (HCC). METHODS: We investigated DNA copy number aberrations in human HCC cell lines using a high-density oligonucleotide microarray. We...
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