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Article

MEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome.

Scientific reports - 20 Apr 2017

Thireau Jérôme, Farah Charlotte, Molinari Nicolas, Bouilloux Fabrice, Torreilles Lucas, Winkelmann Juliane, Scholz Sabine, Richard Sylvain, Dauvilliers Yves, Marmigère Frédéric

Abstract excerpt

Restless Legs Syndrome (RLS) is a genetically complex neurological disorder in which overlapping genetic risk factors may contribute to the diversity and heterogeneity of the symptoms. The main goal of the study was to investigate, through analysis of heart rate variability (HRV), whether in RLS patients the MEIS1 polymorphism at risk influences the sympathovagal regulation in different sleep stages. Sixty-four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28425489
DOI: 10.1038/srep46620
PMCID: PMC5397858

Genes

MEIS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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