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Article

Accurate phenotyping: Reconciling approaches through Bayesian model averaging.

PloS one - 1 Jan 2017

Chen Carla Chia-Ming, Keith Jonathan Macgregor, Mengersen Kerrie Lee

Abstract excerpt

Genetic research into complex diseases is frequently hindered by a lack of clear biomarkers for phenotype ascertainment. Phenotypes for such diseases are often identified on the basis of clinically defined criteria; however such criteria may not be suitable for understanding the genetic composition of the diseases. Various statistical approaches have been proposed for phenotype definition; however our previous...

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PMID: 28423058
DOI: 10.1371/journal.pone.0176136
PMCID: PMC5396931

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