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Article

Linkage mapping of a complex trait in the New York population of the GAW14 simulated dataset: a multivariate phenotype approach.

BMC genetics - 30 Dec 2005

Ghosh Saurabh, Bhattacharjee Samsiddhi, Basu Gourab, Pal Sandip, Majumder Partha P

Abstract excerpt

Multivariate phenotypes underlie complex traits. Thus, instead of using the end-point trait, it may be statistically more powerful to use a multivariate phenotype correlated to the end-point trait for detecting linkage. In this study, we develop a reverse regression method to analyze linkage of Kofendrerd Personality Disorder affection status in the New York population of the Genetic Analysis Workshop 14 (GAW14)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16451627
DOI: 10.1186/1471-2156-6-S1-S19
PMCID: PMC1866768

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