Article
Psychometric precision in phenotype definition is a useful step in molecular genetic investigation of psychiatric disorders.
Translational psychiatry - 30 Jun 2015
Xu M K, Gaysina D, Barnett J H, Scoriels L, van de Lagemaat L N, Wong A, Richards M, Croudace T J, Jones P B
Abstract excerpt
Affective disorders are highly heritable, but few genetic risk variants have been consistently replicated in molecular genetic association studies. The common method of defining psychiatric phenotypes in molecular genetic research is either a summation of symptom scores or binary threshold score...
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