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Article

Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derived Nucleic Acid Sequence.

Chembiochem : a European journal of chemical biology - 18 Jul 2017

Nejad Maryam Imani, Shi Ruicheng, Zhang Xinyue, Gu Li-Qun, Gates Kent S

Abstract excerpt

Hybridization-based methods for the detection of nucleic acid sequences are important in research and medicine. Short probes provide sequence specificity, but do not always provide a durable signal. Sequence-specific covalent crosslink formation can anchor probes to target DNA and might also provide an additional layer of target selectivity. Here, we developed a new crosslinking reaction for the covalent capture...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28422400
DOI: 10.1002/cbic.201700204
PMCID: PMC6139021

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BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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