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Article

Genetic interplay between human longevity and metabolic pathways - a large-scale eQTL study.

Aging cell - 1 Aug 2017

Häsler Robert, Venkatesh Geetha, Tan Qihua, Flachsbart Friederike, Sinha Anupam, Rosenstiel Philip, Lieb Wolfgang, Schreiber Stefan, Christensen Kaare, Christiansen Lene, Nebel Almut

Abstract excerpt

Human longevity is a complex phenotype influenced by genetic and environmental components. Unraveling the contribution of genetic vs. nongenetic factors to longevity is a challenging task. Here, we conducted a large-scale RNA-sequencing-based expression quantitative trait loci study (eQTL) with subsequent heritability analysis. The investigation was performed on blood samples from 244 individuals from Germany and...

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Identifiers

PMID: 28421666
DOI: 10.1111/acel.12598
PMCID: PMC5506416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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