Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetics of human longevity: an intricacy of genes, environment, culture and microbiome.

Mechanisms of ageing and development - 1 Jul 2017

Dato Serena, Rose Giuseppina, Crocco Paolina, Monti Daniela, Garagnani Paolo, Franceschi Claudio, Passarino Giuseppe

Abstract excerpt

Approximately one-quarter of the variation in lifespan in developed countries can be attributed to genetic factors. However, even large population based studies investigating genetic influence on human lifespan have been disappointing, identifying only a few genes accounting for genetic susceptibility to longevity. Some environmental and lifestyle determinants associated with longevity have been identified, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Culture

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Gene Regulatory Networks

Share to Genetics, Aging, and Longevity in Model Organisms

Share to Longevity

Share to Microbiota

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28390822
DOI: 10.1016/j.mad.2017.03.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetics of human longevity: an intricacy of genes, environment, culture and microbiome.PMID 28390822Read ↗

Genetics of Human Longevity Within an Eco-Evolutionary Nature-Nurture FrameworkSemantic proximity Read ↗

Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevitySemantic proximity Read ↗

Untangling the Genetics of Human Longevity—A Challenging QuestSemantic proximity Read ↗

Human longevity: Genetics or Lifestyle? It takes two to tangoSemantic proximity Read ↗

Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies.Semantic proximity Read ↗

Genomics of human longevitySemantic proximity Read ↗

Factors involved in human healthy aging: insights from longevity individualsSemantic proximity Read ↗

Causes, effects, and constraints in the genetics of human longevity.Semantic proximity Read ↗

Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.Semantic proximity Read ↗

Genetics of human longevity: From variants to genes to pathwaysSemantic proximity Read ↗

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.Semantic proximity Read ↗

Integrating the environmental and genetic architectures of mortality and agingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.