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Article

Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.

Oncotarget - 14 Mar 2017

Hong Deli, Messier Terri L, Tye Coralee E, Dobson Jason R, Fritz Andrew J, Sikora Kenneth R, Browne Gillian, Stein Janet L, Lian Jane B, Stein Gary S

Abstract excerpt

Runx1 is a well characterized transcription factor essential for hematopoietic differentiation and Runx1 mutations are the cause of leukemias. Runx1 is highly expressed in normal epithelium of most glands and recently has been associated with solid tumors. Notably, the function of Runx1 in the mammary gland and how it is involved in initiation and progression of breast cancer is still unclear. Here we demonstrate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28407681
DOI: 10.18632/oncotarget.15381
PMCID: PMC5392273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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