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Article

RUNX1 as a Novel Molecular Target for Breast Cancer.

Clinical breast cancer - 1 Aug 2022

Ariffin Nur Syamimi

Abstract excerpt

RUNX1 has long known for its role in hematopoiesis until recently it is implicated in human breast cancer pathogenesis. This has drawn attention in research as elevated expression of RUNX1 has been observed in invasive breast cancer, and mutations of the RUNX1 gene and its binding partner CBFβ have been identified in luminal breast cancer patients, many of which have attributed to the development and progression...

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Identifiers

PMID: 35599145
DOI: 10.1016/j.clbc.2022.04.006

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