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Article

Runx Genes in Breast Cancer and the Mammary Lineage.

Advances in experimental medicine and biology - 1 Jan 2017

Rooney Nicholas, Riggio Alessandra I, Mendoza-Villanueva Daniel, Shore Paul, Cameron Ewan R, Blyth Karen

Abstract excerpt

A full understanding of RUNX gene function in different epithelial lineages has been thwarted by the lethal phenotypes observed when constitutively knocking out these mammalian genes. However temporal expression of the Runx genes throughout the different phases of mammary gland development is indicative of a functional role in this tissue. A few studies have emerged describing how these genes impact on the fate...

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Identifiers

PMID: 28299668
DOI: 10.1007/978-981-10-3233-2_22

Genes

RUNX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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