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Immune overdrive signature in colorectal tumor subset predicts poor clinical outcome

15 Sept 2019

Abstract excerpt

The prognostic value of immune cell infiltration within the tumor microenvironment (TME) has been extensively investigated via histological and genomic approaches. Based on the positive prognostic value of T cell infiltration, Immunoscore has been developed and validated for predicting risk of recurrence for colorectal cancer (CRC). Also, association between a consensus T helper 1 (Th-1) immune response and...

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PMID: 31524634
DOI: 10.1172/jci127046

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