Article
Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers.
British journal of cancer - 9 Aug 2016
Kim Jung Ho, Park Hye Eun, Cho Nam-Yun, Lee Hye Seung, Kang Gyeong Hoon
Abstract excerpt
BACKGROUND: The aim of this study was to reveal the clinicopathological and molecular characteristics of microsatellite instability-high (MSI-H) colorectal cancers (CRCs) showing programmed death ligand-1 (PD-L1) positivity, which are good candidates for anti-PD-1/PD-L1 immunotherapy. METHODS: The PD-L1 expression status of 208 MSI-H CRCs was retrospectively analysed using immunohistochemistry. PD-L1 positivity...
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