Article
[Inherited deficiency of the initiator molecules of the lectin-complement pathway].
Laeknabladid - 1 Oct 2010
Bjarnadottir Helga, Ludviksson Bjorn Runar
Abstract excerpt
The complement system is an important immune system. Its activation results in membranolytic elimination of microbes and opsonization. The classical, alternative and lectin pathways (LP) activate complement. Either mannan-binding lectin (MBL), ficolin-1, ficolin-2 or ficolin-3 initiate the LP through associated serine protease (MASP-2) after binding to microorganisms'surface carbohydrate patterns. Genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
