Interactions Between Genome-Wide Significant Genetic Variants and Circulating Concentrations of 25-Hydroxyvitamin D in Relation to Prostate Cancer Risk in the National Cancer Institute BPC3.

doi:10.1093/aje/kww143

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Article

Interactions Between Genome-Wide Significant Genetic Variants and Circulating Concentrations of 25-Hydroxyvitamin D in Relation to Prostate Cancer Risk in the National Cancer Institute BPC3.

American journal of epidemiology - 15 Mar 2017

Dimitrakopoulou Vasiliki I, Travis Ruth C, Shui Irene M, Mondul Alison, Albanes Demetrius, Virtamo Jarmo, Agudo Antonio, Boeing Heiner, Bueno-de-Mesquita H Bas, Gunter Marc J, Johansson Mattias, Khaw Kay-Tee, Overvad Kim, Palli Domenico, Trichopoulou Antonia, Giovannucci Edward, Hunter David J, Lindström Sara, Willett Walter, Gaziano J Michael, Stampfer Meir, Berg Christine, Berndt Sonja I, Black Amanda, Hoover Robert N, Kraft Peter, Key Timothy J, Tsilidis Konstantinos K

Abstract excerpt

Genome-wide association studies (GWAS) have identified over 100 single nucleotide polymorphisms (SNPs) associated with prostate cancer. However, information on the mechanistic basis for some associations is limited. Recent research has been directed towards the potential association of vitamin D concentrations and prostate cancer, but little is known about whether the aforementioned genetic associations are...

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PMID: 28399564
DOI: 10.1093/aje/kww143
PMCID: PMC5856084

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