Article
Vitamin D-associated genetic variation and risk of breast cancer in the breast and prostate cancer cohort consortium (BPC3).
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2015
Mondul Alison M, Shui Irene M, Yu Kai, Weinstein Stephanie J, Tsilidis Konstantinos K, Joshi Amit D, Agudo Antonio, Berg Christine D, Black Amanda, Buring Julie E, Chasman Daniel I, Gaudet Mia M, Haiman Christopher, Hankinson Susan E, Henderson Brian E, Hoover Robert N, Hunter David J, Khaw Kay-Tee, Kühn Tilman, Kvaskoff Marina, Le Marchand Loic, Lindström Sara, McCullough Marjorie L, Overvad Kim, Peeters Petra H, Riboli Elio, Ridker Paul M, Stram Daniel O, Sund Malin, Trichopoulos Dimitrios, Tumino Rosario, Weiderpass Elisabete, Willett Walter, Kraft Peter, Ziegler Regina G, Albanes Demetrius
Abstract excerpt
BACKGROUND: Two recent genome-wide association studies (GWAS) identified SNPs in or near four genes related to circulating 25-hydroxyvitamin D [25(OH)D] concentration. To examine the hypothesized inverse relationship between vitamin D status and breast cancer, we studied the associations between SNPs in these genes and breast cancer risk in a large pooled study of 9,456 cases and 10,816 controls from six cohorts....
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