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Vitamin D Pathway and Other Related Polymorphisms and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial.

Cancer prevention research (Philadelphia, Pa.) - 1 Jun 2020

Torkko Kathleen, Till Cathee, Tangen Catherine M, Goodman Phyllis J, Song Xiaoling, Schenk Jeannette M, Lucia M Scott, Peters Ulrike, van Bokhoven Adrie, Thompson Ian M, Neuhouser Marian L

Abstract excerpt

Vitamin D may influence prostate cancer risk, but evidence is inconsistent. We conducted a nested case-control study in the Prostate Cancer Prevention Trial (PCPT). Cases (n = 1,128) and controls (n = 1,205) were frequency matched on age, first-degree relative with prostate cancer, and PCPT treatment arm (finasteride/placebo); African-Americans were oversampled and case/control status was biopsy confirmed. We...

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Identifiers

PMID: 32102946
DOI: 10.1158/1940-6207.CAPR-19-0413
PMCID: PMC7272271

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