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Article

Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study.

Journal of the National Cancer Institute - 2 May 2012

Shui Irene M, Mucci Lorelei A, Kraft Peter, Tamimi Rulla M, Lindstrom Sara, Penney Kathryn L, Nimptsch Katharina, Hollis Bruce W, Dupre Natalie, Platz Elizabeth A, Stampfer Meir J, Giovannucci Edward

Abstract excerpt

BACKGROUND: The association of vitamin D status with prostate cancer is controversial; no association has been observed for overall incidence, but there is a potential link with lethal disease. METHODS: We assessed prediagnostic 25-hydroxyvitamin D [25(OH)D] levels in plasma, variation in vitamin D-related genes, and risk of lethal prostate cancer using a prospective case-control study nested within the Health...

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Identifiers

PMID: 22499501
DOI: 10.1093/jnci/djs189
PMCID: PMC3341310

Genes

VDR
RXRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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