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Article

Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.

Carcinogenesis - 1 May 2009

Ahn Jiyoung, Albanes Demetrius, Berndt Sonja I, Peters Ulrike, Chatterjee Nilanjan, Freedman Neal D, Abnet Christian C, Huang Wen-Yi, Kibel Adam S, Crawford E David, Weinstein Stephanie J, Chanock Stephen J, Schatzkin Arthur, Hayes Richard B

Abstract excerpt

We systematically investigated the association of 48 SNPS in four vitamin D metabolizing genes [CYP27A1, GC, CYP27B1 and CYP24A1] with serum 25-hydroxyvitamin D [25(OH)D] and 1,25-dihydroxyvitamin D [1,25(OH)(2)D] levels and the association of these SNPS and an additional 164 SNPS in eight downstream mediators of vitamin D signaling [VDR, RXRA, RXRB, PPAR, NCOA1, NCOA2, NCOA3 and SMAD3] with prostate cancer risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19255064
DOI: 10.1093/carcin/bgp055
PMCID: PMC2675652

Genes

VDR
NCOA1
NCOA2
NCOA3
RXRA
RXRB
SMAD3

Provenance

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