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Article

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.

Neuro-oncology - 1 Sept 2017

Vitucci Mark, Irvin David M, McNeill Robert S, Schmid Ralf S, Simon Jeremy M, Dhruv Harshil D, Siegel Marni B, Werneke Andrea M, Bash Ryan E, Kim Seungchan, Berens Michael E, Miller C Ryan

Abstract excerpt

BACKGROUND: Gliomas are diverse neoplasms with multiple molecular subtypes. How tumor-initiating mutations relate to molecular subtypes as these tumors evolve during malignant progression remains unclear. METHODS: We used genetically engineered mouse models, histopathology, genetic lineage tracing, expression profiling, and copy number analyses to examine how genomic tumor diversity evolves during the course of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28398584
DOI: 10.1093/neuonc/nox050
PMCID: PMC5570221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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