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Article

Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.

2020-08-07

Abstract excerpt

<title>Abstract</title> <p>Patients with medulloblastoma are typically treated with a narrow range of therapies, but may experience widely divergent outcomes; 80-90% become long-term survivors while 20% develop incurable recurrence. Transcriptomic profiling has identified four subgroups with different recurrence risks, but outcomes remain variable for individual patients within each subgroup. To gain new insight...

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Literature Corpus work
ed77d183-390e-54ce-a70b-d44b1e860336
DOI
10.21203/rs.3.rs-50396/v1
Open publication

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Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.DOI 10.21203/rs.3.rs-50396/v1
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